Venom dons a striking red-and-blue costume and adopts a new identity, igniting public debate over whether the city’s latest Spider-Man is a welcomed hero or a reviled symbiote. Luke Cage and Doctor Octopus engage in a brutal showdown, challenging the symbiote’s legitimacy in New York. The issue also features a standalone origin story for an even newer Venom variant and a nostalgic flashback crafted by the team behind the classic *Amazing Spider-Man* #252.